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Cur@SF NPs alleviate Friedreich's ataxia in a mouse model through synergistic iron chelation and antioxidation

IS: PGA 13 C 5 was obtained from MedChemExpress (Monmouth Junction, NJ, USA)

In vitro, we could demonstrate that the ENL YEATS domain interacts with CRBNDDB1 (damage-specific DNA-binding protein 1) and the newly reported CRBN midi construct 41 but only in the presence of the compound (Fig