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Most of the porphyrias are inherited and result from a faulty gene, which leads to difficulty making a chemical called haem a constituent of many important proteins in the body

Exp Mol Med 55 , 10991109 (2023)

doi: 10.1586/ern.10.185

3.3.2 ROS promotes HCC metastasis ROS not only drive HCC proliferation but also promote migration and metastasis through the activation of redox-sensitive signaling pathways such as NF-B, ERK, AKT, and c-Jun [91]