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Although there is growing evidence supporting the use of curcumin, it should be noted that most studies have been conducted over short periods, typically involve small sample sizes, and curcumin is consistently administered in combination with DMARDs and at variable doses [6062]

Thus, the S-nitroso-acetyl-lipoate modification likely represents S-nitrosation occurring after the enzyme is inhibited at the acetylated state

Delmas D., Hermetet F., and Aires V., PD1/PDL1 Checkpoints and Resveratrol: A Controversial New Way for a Therapeutic Strategy, Cancers (Basel) 13, no