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In a 2021 study in obese mice, 5-amino-1MQ administration caused significant body mass reductions in the rodents, who achieved body composition and liver adiposity parameters that were comparable to the lean mice in the control group
D.FennesseyP
Machiraju, P., Wang, X., Sabouny, R., Huang, J., Zhao, T., Iqbal, F., King, M., Prasher, D., Lodha, A., Jimenez-Tellez, N., Ravandi, A., Argiropoulos, B., Sinasac, D., Khan, A., Shutt, T
Final results of a multicenter phase II study of the purine nucleoside phosphorylase (PNP) inhibitor forodesine in patients with advanced cutaneous T-cell lymphomas (CTCL) (Mycosis fungoides and Szary syndrome)
