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Cryopreservation induces excessive generation of ROS and causes sperm cell damage with extreme sensitivity to ROS owing to limited cytoplasm, low antioxidant capacity, and higher level of polyunsaturated fatty acids (PUFA) in plasma membrane of sperm cells

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a prospective study demonstrated cognitive impairment (overt or subclinical) in 42% of cirrhotics without infection, in 79% with infection and in 90% with sepsis and systemic inflammatory response [30]