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Description
In general, TD in the brain leads to oxidative stress, lactic acidosis, neuroinflammation, and excitotoxicity as a result of a decrease in the activity of ThDP-dependent enzymes, as well as other thiamine-dependent processes [48]

Interleukin-1beta induces mtdna release to activate innate immune signaling via cgas-sting

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doi: 10.1089/thy.2023.0556
