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Description
The most characterized transcription factors involved in the regulation of EMT include snail family transcriptional repressor (SNAIL)1, zinc finger E-box binding homeobox 1 (ZEB1), and twist family bHLH transcription factor 1 (TWIST1) [33, 34]

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Although the retro-inverso approach may fail to accurately reproduce biological function in the context of helical structures (e.g., p53 or HIV-1 proteins), certain exceptionssuch as the binding of a p53-derived retro-inverso peptide to its regulator MDM2demonstrate that well-designed D-peptides can, in specific cases, effectively mimic the function of the original peptide