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4.1.1 Short-chain fatty acids Short-chain fatty acids (SCFAs), the primary end products of anaerobic bacterial fermentation of dietary fibers in the mammalian colon, can reach concentrations of 50200 mM, with acetate (C2), propionate (C3), and butyrate (C4) accounting for approximately 95% of total SCFAs ( Bacteroidetes and Firmicutes serve as predominant producers of SCFAs: Bacteroidetes primarily generates acetate and propionate, whereas Firmicutes predominantly produces butyrate

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