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The FSP1-CoQ10-NADPH pathway could cooperate with GSH and GPX4 to scavenge lipid peroxidation intermediates [49, 50]

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28,29,30 NOX-mediated ROS broadly and specifically regulate various redox-sensitive signaling pathways involved in cancer progression via stimulating oncogenes, such as Src and Ras, and inactivating tumor suppressor proteins, such as TP53 and PTEN

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