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Secondary effects from IGF-1 therapy were reported after administration of doses higher than 6080 g/kg/day

Han, J., Xu, H., Paleti, S

In STEP 1 and STEP 3, patients on semaglutide lost 14.816.0% BW compared to 2.45.7% in the placebo group at 68 weeks 26,27

For brain repair applications where multiple peptides may be used across extended timelines, understanding the total financial commitment upfront prevents the common mistake of starting a protocol that cannot be sustained long enough to produce meaningful results