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Serine 408 phosphorylation is a molecular switch that regulates structure and function of the occludin -helical bundle

To explore how these mutations impact systemic metabolism, we investigated serum metabolomic profiles of male (N=6) and female (N=11) PD patients carrying LRRK2 mutations, compared with age- and sex-matched HCs (male, N=23

The constituent amino acids are then transported into the cells where they are available to make GSH

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