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Studies have shown that hesperidin can reduce oxidative stress markers like malondialdehyde (MDA) by 40% and increase the activity of antioxidant enzymes such as superoxide dismutase (SOD) in vascular cells

It is capable of inhibiting stretch-activated and voltage-gated calcium channels

This suggests that fermentable fibers like inulin may be especially beneficial for IBS-C patients, likely through modulation of the gut microbiota and the gut-brain axis

The observed basic architecture may provide the possibility to predict the role of an immune cell based on its localization within the given inflammatory setting