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Lancet 397 , 194 (2021)
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Only female individuals showed reduced nicotine intake during chronic oral administration ( 7 -nAChR knockout models collectively suggest a dissociation from canonical 7 -mediated pathways in eliciting this behavioral modulation ( In conclusion, the molecular structure, diverse combinations, widespread distribution, and functional variety of nAChRs collectively underpin their central role in nicotine addiction (Table 1)
