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Description
In addition to its direct antitumor effects, daratumumab exerts an indirect immunomodulatory role by eliminating CD38 + immunosuppressive cell types (Treg, Breg and myeloid-derived suppressor cells) in the tumor microenvironment (TME), thereby promoting T-cell proliferation and effector functions [44]
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T., Sonne, N., Andreassen, K
Still others are most effective during later healing phases to optimize tissue remodeling and minimize scar formation
