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[DOI] [PMC free article] [PubMed] [Google Scholar] Groves C.E., Lock E.A., Schnellmann R.G

3 Taus role in neurodegenerative disease A recent NINDS consensus document indicated that CTE is likely to occur in the years to decades following rTBI

So if something goes wrong and the GSSG accumulates, it inhibits an enzyme that relies on the correct oxidation of the ER environment to operate a protein quality control system. Moreover, they discovered, when misfolded proteins dont pass quality control, they wont get exported, so they too pile up in the ER

They should take daily multivitamins, calcium, and vitamin B12 supplements