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Lentivectors have been developed from primate lentiviruses, such as the wild-type human immunodeficiency virus type 1 and non-primate lentiviruses, such as the equine infectious anemia virus, by progressively removing most of the viral genes from the vector genome to limit the risk of producing replication-competent viral particles (Cronin et al

Chronic neuroinflammation also plays a significant role in Parkinsons disease progression (37, 38)

It promotes mitochondrial fusion and cell survival by upregulating mitochondrial prohibitin 2 and optic atrophy 1 protein levels (72)

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