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Indeed, some studies indicated a crosstalk between 25[OH]D and GSH, where GSH was reported to positively up-regulate the bioavailability of 25[OH)D, 46 and, on the other hand, 25[OH)D was shown to up-regulate GSH production in vitro in U937 monocytes exposed to high glucose

however, this reduction did not reach statistical significance

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Abstract The evidence to date, coupled with advances in immunology and genetics has afforded the field an unparalleled opportunity to investigate the hypothesis that a subset of patients with schizophrenia may manifest an immunophenotype, toward new potential diagnostics and therapeutics to reduce risk, alleviate symptoms, and improve quality of life in both at-risk populations and patients with established schizophrenia