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Methycobal injection may worsen the symptoms of this condition

A separate line of investigation, work by Pollard and colleagues, demonstrated that GHK-Cu could reverse detrimental changes in irradiated cultured human fibroblasts: cells exposed to significant radiation and then treated with GHK-Cu at very low concentrations displayed a growth pattern and growth-factor secretion profile comparable to non-irradiated control cells, including increased secretion of bFGF and VEGF

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Notably, while neuronal elements (axons, neurons, dendrites, and synapses) are also damaged to a significant extent (Mck et al., 2021), demyelination is a constant finding in both white and gray matter regions pointing to the myelinating unit (the myelin sheath and oligodendrocyte) as a key target in this disease