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Abstract We here report the history of cerebrotendinous xanthomatosis (CTX) research, from the description of the first cases, until the recent developments

Loss of hACE2 in the vasculature may lead to endothelial dysfunction, inflammation and aggravate atherosclerosis and diabetes 284,310

In contrast, SEPT9-NCmut1 (I281D and M288D) and SEPT9-R561E formed only tetramers, due to the impaired NC-interface as previously reported 21,24

Johnson B, Haymaker CL, Parra ER, Soto LMS, Wang X, Thomas JV, Dasari A, Morris VK, Raghav K, Vilar E, Kee BK, Eng C, Parseghian CM, Wolff RA, Lee Y, Lorenzini D, Laberiano-Fernandez C, Verma A, Lang W, Wistuba II, Futreal A, Kopetz S , Overman MJ