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Curr Protoc Bioinf (2016) 2016:14.10.1114.10.91

In addition, non-enzymatic reactions which are integral parts of the metabolic networks with essential roles in cellular metabolism, cannot be captured by the enzyme activity-based metabolomics approaches

This finding has been controversial but a transcriptomic analysis of acutely isolated astrocytes has recently confirmed that PAG is indeed expressed by astrocytes (Lovatt et al
