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BMI1, a component of PRC1 that promotes chromatin compaction and gene silencing through E3 ligase activity mediated by RING1A/B (H2AK119ub), is silenced in late-onset sporadic AD brain (cortical neuron)
de Faria SM, de Morais FD, Tumas V, et al
Therapeutic activity of DCC-2036, a novel tyrosine kinase inhibitor, against triple-negative breast cancer patient-derived xenografts by targeting AXL/MET
doi: 10.1016/S1474-4422(13)70110-8
