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Description
Hypoxia-inducible factor-prolyl hydroxylase inhibitors in the treatment of anemia of chronic kidney disease
Fibroblast growth factor 21 (FGF21) will be activated by glutamine depletion stress by activating peroxisome proliferatoractivated receptor coactivator-1 (PGC-1)
Furthermore, ammonia release from tumor cells involved in glutaminolysis acts as an autocrine and paracrine signal, promoting autophagy and protecting cells in different tumor regions from internal or environmental stress [20]
Kang G, Li G, Liu G, Xu W, Peng X, Wang C, Zhu Y, Guo T
