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Conversely, super-fast or rapid metabolizers (individuals with highly active CYP isoforms) can have altered drug responses by due to substantially lowered active drug lifespan

Rigorous evaluation of RNA-small molecule binding by BIVID-MaP may help reassess existing compounds and optimize drug discovery for individuals with specific genetic variants

a complementary reactive group that is protected can include COOR PGO or NHR PGN , where R PGO is an O-protecting group (e.g., a carboxyl protecting group), and R PGN is an N-protecting group

For the analysis, the FISH score was set at 2+ minimum copies/cell, and phenotypes were defined by exclusive channels and according to the round of imaging