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Description
Spector A, Roy D
In Alzheimers disease, astrocytic dysfunction impairs glutamate clearance via downregulated GLT-1/GLAST and reduces lactate production through decreased lactate dehydrogenase A (LDHA) activity, leading to neuronal energy deficits and exacerbated NMDA receptor excitotoxicity
The Hidden Problem: Poor B12 Absorption Here is where many people get stuck
The polymerization is monitored visually (by observing changes, typically the darkening of the solution) and spectrophotometrically (by tracking the absorbance peaks around 305 and 480 nm denoting the intermediate species involved in PDA formation)
