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If melanocytes have been lost entirely (as in fully white hair), stimulation can't produce pigment because there are no melanocytes left to activate

Chronic CNS overstimulation elevates cortisol, accelerates systemic fatigue, and erodes the deep sleep stages during which natural growth hormone peaks to preserve lean muscle tissue

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These effects suggest that ketogenic diets may increase the efficacy of cancer radiotherapy, chemotherapy, and immunotherapy [401]
