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Challenges : Regulatory scrutiny in EU and US markets requiring full traceability and safety documentation

KPV should not be treated as a proven cure for inflammatory bowel disease, autoimmune disease, histamine intolerance, MCAS, chronic pain, or general inflammation

doi:10.1074/jbc.M809338200, PMID: 19176520 Suthanthiran M, Anderson ME, Sharma VK, Meister A (1990) Glutathione regulates activation-dependent DNA synthesis in highly purified normal human T lymphocytes stimulated via the CD2 and CD3 antigens

Patients with neurological symptoms require more intensive treatment with alternate-day injections until improvement plateaus, and may need more frequent maintenance dosing