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Description
APAP, Acetaminophen

FIGURE 2 The most damaging oxidative insult occurs upon reperfusion, where the sudden reintroduction of oxygen paradoxically triggers a massive burst of ROS and reactive nitrogen species (RNS)

The risk is higher if you use more than directed or for longer than directed

Proteomic and metabolite profiling reveals profound structural and metabolic reorganization of adipocyte mitochondria in obesity
