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Hepatitis B virus stimulates G6PD expression through HBx-mediated Nrf2 activation

Agents that block ADAMTS-5, neutralize nerve growth factor, or reduce cellular senescence have shown disease-modifying potential (Jiang et al., 2021)

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Further investigation into the testicular microenvironment using a co-culture system of senescent TM3 Leydig cells and GC-1 spg spermatogonia revealed that H2O2-induced senescent TM3 cells secreted increased levels of SASP factors, particularly IL-6 and TGF-