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Cyclodextrins are mainly used as excipients in parenteral formulations, exploiting their solubility-enhancing properties

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part of the electromagnetic spectrum with wavelengths from 100 nm - 400 nm UV-A Ultraviolet radiation with longer wavelengths (315-400 nm) UV-B Ultraviolet radiation with shorter wavelengths (280-315 nm) AP-1 Activator protein 1

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Interestingly, active wildtype p53 is known to inhibit the transcription of genes involved in polyamine synthesis ( ARG1, ODC1) and promotes transcription of genes involved in polyamine catabolism ( SSAT) , which then increases ROS [41]

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Under these uncontrolled conditions, the concentrations of ROS exceed the capacity of local antioxidant molecules neutralize them (112, 115, 150), resulting in a buildup of ROS O and H 2 O 2 , and also malondialdehyde, at the site of the ovary and in follicular fluid and peritoneal fluid (103, 105, 106, 108, 111, 112)

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