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[DOI] [PubMed] [Google Scholar] 212.Garg R, Gupta S, Maru GB

J Dermatol Sci 86(2):e8 Madonna S, Scarponi C, Sestito R, Pallotta S, Cavani A, Albanesi C (2010) The IFN-Dependent suppressor of cytokine signaling 1 promoter activity is positively regulated by IFN regulatory factor-1 and Sp1 but repressed by growth factor independence-1b and Krppel-Like Factor-4, and It Is dysregulated in psoriatic keratinocytes

The balance between acetylation and deacetylation is important for the regulation of gene function

The compound does not appear to cause physiological dependence, but the durability of its effects has not been studied in withdrawal protocols.
