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Some claim that excipients added to vaccines are the reason that MTHFR C677T variant carriers should not be vaccinated

Lysosomotropic agents Lysosomotropic agents, such as chloroquine, ammonium chloride, and antibiotics like quinolones, are weak bases that can easily cross cell membranes and accumulate within lysosomes

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Further, an LPS administration model of systemic inflammation in sepsis in conjunction with convulsant PTZ treatment in mice increased seizure susceptibility, which was attenuated with NOX2 genetic ablation and inhibition (Huang et al., 2018)