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Key Focus: Brightening, Anti-Pigmentation, Deep Hydration
biochemically, there is intracellular glutathione (GSH) depletion and decreased activity of glutathione peroxidase 4 (GPX4), lipid peroxides cannot be metabolized by the GPX4-catalyzed reduction reaction, and Fe 2+ oxidizes lipids in a Fenton-like manner, resulting in a large amount of ROS, which promotes ferroptosis 3,6
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doi: 10.1111/j.1365-2222.1991.tb00831.x
