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Kayode OT, Rotimi DE, Olaolu TD, Adeyemi OSJB, Pharmacotherapy
Although residues C32 and C88 of PfGrx are redox-inactive during the monothiol mechanism, they both facilitate the deglutathionylation of GSSR substrates

Scientific References Berberine as a Bioactive Alkaloid: Multi-Omics Perspectives on Its Role in Obesity Management

This could reflect the effects of the decrease in IRS-1mediated insulin signaling in adipose or a difference in the balance of insulin/IGF-1 action on adipocyte differentiation (46)
