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2-APQC, a small-molecule activator of Sirtuin-3 (SIRT3), alleviates myocardial hypertrophy and fibrosis by regulating mitochondrial homeostasis

Published human studies (Dhillo et al., JCEM, 2005) used IV bolus doses and observed rapid hormonal responses

Am J Respir Crit Care Med 181:797805

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