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Constipation, diarrhea, loss of appetite, or flatulence

One cause can be liver stress due to your hypothyroid state, meaning it wont be doing a good job clearing out your excess B12

In preclinical studies, healthy mice, CKD rats, and diabetic mice treated with NA, NAM, or NMN showed increased NAD + levels in the kidney 297299

Post-injection care is straightforward: Stay hydrated for the remainder of the day Avoid rubbing or massaging the injection site aggressively Apply a cold compress if swelling or soreness develops at the injection site Monitor for signs of allergic reaction (hives, difficulty breathing, dizziness) for at least 30 minutes Contact your provider or seek emergency care if you experience chest tightness, significant swelling, or breathing difficulty Strenuous exercise can resume the same day for most patients, though some prefer to wait until the following morning if injection-site soreness is noticeable