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Similar content being viewed by others Introduction With the exception of a few instances, such as cleavage divisions of a fertilized zygote in early embryogenesis, cell proliferation is linked to the biomass accumulation

Inhibition of histone demethylase JMJD1A improves anti-angiogenic therapy and reduces tumor-associated macrophages
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10: e034090

Several studies have shown that SDH-deficient cells exhibit increased tumorigenesis and that this increase is reversed by the addition of -KG, supporting the idea that succinate accumulation contributes to tumorigenesis through epigenetic modification 100