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In ME/CFS, the integrity of the BBB may be compromised, thereby allowing peripheral inflammatory mediators to infiltrate the brain and induce neuroinflammation

The primary concern involves shipping during extreme cold or heat, where freeze-thaw cycles could damage peptide integrity

Results PTM-dependent ligandability profiling in human cells To investigate changes in protein ligandability as a function of phosphorylation status, we aimed to broadly perturb phosphorylation while minimizing potential convoluting proteomic alterations

Choi, K.-C., Kim, S.-H., Ha, J.-Y., Kim, S.-T
