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[] Accelerated detoxification N-acetylcysteine (NAC) is the main antidote for paracetamol overdose, acting by restoring glutathione levels, [] Figure 3 illustrates the mechanism of paracetamols action, showing its metabolic pathways, including the production of NAPQI and its detoxification by glutathione

10.1186/s12951-023-01854-x 282 ZhangN.LinR.GaoW.XuH.LiY.HuangX.et al (2025)

Coburn LA , Singh K, Asim M, Barry DP, Allaman MM, Al-Greene NT, Hardbower DM, Polosukhina D, Williams CS, Delgado AG, Piazuelo MB, Washington MK, Gobert AP, Wilson KT

In terms of tumor type coverage, trials related to solid tumors account for a high proportion, with only 1 trial focusing on hematological malignancies
