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Alveolar type II cells from ethanol-fed animals form a more permeable monolayer and have decreased alveolar fluid clearance and increased protein leak across the monolayer

Alternatively, in vitro culture of constructs 52,90 can promote increased deposition and organization of ECM, further elevating mechanical properties of these scaffolds (Fig

During protein folding stress, the sirtuin SIRT7 also plays an important role by contributing to repressing nuclear respiratory factor 1 (NRF1) activity, a major transcriptional regulator of mitochondrial genes

[DOI] [PubMed] [Google Scholar] 204.Miller ER, 3rd, Paston-Barriuso R, Dalal D, Riemersma RA, Appel LJ, Guallar E
