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This effect may be explained by the inhibition of proinflammatory pathways such as NF-B, as well as reduction in the immune cells activation responsible for free radical generation

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Kolarow R, Kuhlmann CRW, Munsch T, Zehendner C, Brigadski T, Luhmann HJ, Lessmann V (2014) BDNF-induced nitric oxide signals in cultured rat hippocampal neurons: time course, mechanism of generation, and effect on neurotrophin secretion