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Description
a 2022 systematic review in Nutrients (PMID 36364865) covers select dietary supplement ingredients, including Vitamin C, in the context of supporting normal immune function Hyaluronic Acid: commonly associated with skin hydration

Common triggers include: Sun exposure Acne and inflammation Hormonal changes (melasma) Skin irritation When tyrosinase becomes overactive, it leads to visible dark spots and uneven tone

This can also enhance gut barrier integrity via tight junction protein expression

hence, clinical evidence remains lacking
