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This effect is believed to be due to IGF-1 suppression of insulin secretion, which leads to augmented lipolysis in adipose tissue and promotion of FFA use by muscle

Polyethylene Glycol Immunogenicity in Nanomedicine

10.1089/ars.2013.5346 23 ChandranS.GuoT.TolliverT.ChenW.MurphyD
