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Impact of growth hormone-related mutations on mammalian aging

Hafez E, Abd El-Aziz NM, Darwish AMG, Shehata MG, Ibrahim AA, Elframawy AM, Badr AN (2021) Validation of New ELISA technique for detection of aflatoxin B1 contamination in food products versus HPLC and VICAM

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Results GSH depletion induces cell death in RPE cells To evaluate the effect of GSH depletion on the RPE cells, we used three different approaches: depletion of Cys 2 from cell culture media, treatment with buthionine sulphoximine (BSO, 1000 M) to block de novo synthesis of GSH, or treatment with erastin (10 M), an inhibitor of system x c 1