hepatitis c virus life cycle and lipid metabolism Replication of Hepatitis C virus hijacks host

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[Note: This structure is called CURL, the compartment for uncoupling of receptor and ligand.] [5] The receptors can be recycled, whereas the lipoprotein remnants in the vesicle are transferred to lysosomes and degraded by lysosomal acid hydrolases, releasing free cholesterol, amino acids, fatty acids, and phospholipids

Meanwhile, a wealth of literature has long been available about the biotransformation of xenobiotics, notably by gut bacteria (reviewed in Sousa et al., 2008