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[DOI] [PubMed] 83.Pennone V, Angelini E, Sarlah D, Lovati AB

RAR equivalent dose (RARED) and RAR factor (RARF) Equation 1 is used to calculate RARF values, which are then compiled in Table 4

The data presented demonstrate a restoration of FcR binding to the aglycosylated Fc domain as a result of immune complex formation, consistent with previous observations for Fc silenced constructs ( Although the totality of the data supports the immune complex hypothesis described above, we cannot rule out an alternative or supplemental mechanism, such as binding of AMG 966 to TL1A and/or TNF on the surface of antigen presenting cells