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Given the clear relationship between IGF-1 and aging, we reasoned that IGF-1R mAbs could provide a translational tool to mimic the beneficial effects reported by reduced signaling in this pathway

M., & Grinspoon, S

Biochemistry 37 , 1323913249 (1998)

Because it is an FDA-approved drug that requires direct physician supervision and safety oversight, benralizumab is generally prescribed for patients with uncontrolled asthma who remain symptomatic despite high-dosage inhaled corticosteroids, therapeutic drug agents, or immunosuppressive therapy
