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While the body produces glutathione on its own, factors like stress, pollution, poor diet, and aging can lead to a decline in its levels

They are generally smaller molecules with broader mechanisms of action

Post-Translational Modification of GPX4 is a Promising Target for Treating Ferroptosis-Related Diseases

However, such resistance in these patients may be caused by several other factors, including esophageal mucosal hypersensivity, bile acid reflux, abnormal esophageal motility, gastric motility disorders and rather than from acid reflux (10)
