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For people with life-threatening (fulminant) colitis (more than 10 stools per day with continuous blood, enlargement of the colon with fever, elevated heart rate, and laboratory tests indicating inflammation), hospitalization is required

A prospective multicenter phase I/II clinical trial to evaluate safety and efficacy of NOVOCART Disc plus autologous disc chondrocyte transplantation in the treatment of nucleotomized and degenerative lumbar disc to avoid secondary disease: study protocol for a randomized controlled trial

doi: 10.1016/j.smrv.2004.03.005 20 BornJMuthSFehmHL

B12 injections can administered subcutaneously (under the skin) or intramuscularly (into a muscle)