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European Journal of Dermatology , 30(6), 639-651

The results confirmed that parabulbar injections are unnecessary for the desired effect and that Epitalon is more effective when administered during pregnancy and throughout life [19]

Specifically, the peptide downregulates inflammatory genes including interleukin-1, tumor necrosis factor-, and nuclear factor-B, while upregulating protective genes such as those encoding antioxidant enzymes, DNA repair proteins, and extracellular matrix components
