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Description
It has been demonstrated that xCT deficiency or inhibition suppresses cell proliferation and tumor growth and induces cell death by apoptosis or cell death mediated by accumulation of lipid ROS or lipid peroxidation, known as ferroptosis (231234)
Hussain, A., Mojgani, N., Koser, N., Siddiqui, M
Administration of GbE before PTZ injection significantly decreased ( p 0.05) the seizure score on days 33 and 35
The kinase ATM also controls sensitivity to ferroptosis through regulation of ferritin abundance (Chen et al., 2020b)
